Sex differences in autoimmune diseases
نویسندگان
چکیده
منابع مشابه
Sex-based differences in autoimmune diseases.
Autoimmune diseases are characterized by an exaggerated immune response leading to damage and dysfunction of specific or multiple organs and tissues. Most autoimmune diseases are more prevalent in women than in men. Symptom severity, disease course, response to therapy and overall survival may also differ between males and females with autoimmune diseases. Sex hormones have a crucial role in th...
متن کاملSex hormones, autoimmune diseases, and immune responses.
syndrome lies in some micro-organism as yet undiscovered. After all, Legionella pneumophila, Borrelia burgdorferi, and Helicobacter pylon were unknown pathogens 15 years ago. The urethral syndrome is common and distressing and causes much unhappiness. It inevitably results in the overuse of antibiotics and proliferation of bacteria resistant to antibiotics. It deserves more thorough investigati...
متن کاملRole of environment and sex differences in the development of autoimmune diseases: a roundtable meeting report.
Autoimmune diseases (ADs) impose substantial health and financial burdens in the United States and in many parts of the world. Women are disproportionately affected by many of these disorders, which often contribute to lifelong disabilities. While the number of patients with some ADs appears to be rising, the complexities of conducting epidemiological studies prevent a thorough understanding of...
متن کاملSex Differences in Pediatric Infectious Diseases
The success of the immune response is finely balanced between, on the one hand, the need to engage vigorously with, and clear, certain pathogens; and, on the other, the requirement to minimize immunopathology and autoimmunity. Distinct immune strategies to achieve this balance have evolved in females and males and also in infancy through to adulthood. Sex differences in outcome from a range of ...
متن کاملSex, MHC and complement C4 in autoimmune diseases.
Autoimmune diseases are estimated to affect 10-50 million people in the United States, and untold millions worldwide. Nearly 80% of all people with autoimmune diseases are women, and a strong association of these diseases with MHC genes has been known for some time. However, very little is known about what causes autoimmune diseases or the factors that lead to disease recurrence. The sex-associ...
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ژورنال
عنوان ژورنال: Biology of Sex Differences
سال: 2011
ISSN: 2042-6410
DOI: 10.1186/2042-6410-2-1